ProstaRedox
ProstaRedox is a dietary supplement formulated to support redox balance and enhance antioxidant defenses, particularly for men at high risk of prostate cancer or those undergoing treatment. It combines natural compounds—curcumin, quercetin, resveratrol, and selenium—that influence the thioredoxin system and thioredoxin reductase 2 (TrxR2), an enzyme essential for maintaining cellular redox homeostasis.
Curcumin, derived from turmeric extract, is included at 500 mg per serving and is standardized to 95% curcuminoids. Renowned for its antioxidant properties, curcumin inhibits TrxR2, potentially reducing cancer cell proliferation by inducing oxidative stress. Quercetin, present at 250 mg per serving and standardized to 95% quercetin dihydrate, supports antioxidant defenses and modulates inflammation, both crucial for managing cancer. Resveratrol, provided at 200 mg per serving from Japanese knotweed extract with 50% trans-resveratrol, influences cellular redox states and TrxR2 activity, offering cardiovascular and cellular protection. Selenium, which is included as L-selenomethionine at 200 mcg per serving, is vital for TrxR activity and overall redox balance. Piperine, extracted from black pepper and standardized to 95%, is included at 10 mg per serving to enhance the absorption of curcumin and other polyphenols.
ProstaRedox supports prostate health through its antioxidant formulation. Curcumin impacts cellular signaling pathways involved in inflammation and oxidative stress, potentially reducing cancer cell proliferation. Quercetin modulates TrxR2 and related enzymes, reducing oxidative damage and supporting anti-inflammatory processes. Resveratrol improves redox states and indirectly influences TrxR2 activity. Selenium ensures optimal TrxR function and protects cells from oxidative damage. Piperine enhances the bioavailability of curcumin and quercetin, ensuring they reach therapeutic levels in the bloodstream.
The supplement is recommended for men at high risk of prostate cancer, those undergoing prostate cancer treatment, and men in post-treatment recovery. It can also be used by anyone seeking a comprehensive antioxidant supplement. The suggested dosage is one to two capsules daily, taken with meals to improve absorption and minimize gastrointestinal discomfort. For best results, take ProstaRedox consistently at the same time each day.
Curcumin and quercetin have low bioavailability due to rapid metabolism, but piperine enhances their absorption. Once absorbed, these compounds target tissues with high oxidative activity, such as the liver and prostate. Curcumin and quercetin undergo extensive metabolism and are excreted via bile and urine, while selenium is excreted through urine, feces, and sweat.
ProstaRedox is generally well-tolerated. However, individuals with hypersensitivity to any of the components should avoid it. Those with a history of kidney stones or hypercalcemia should use it cautiously. Common side effects include mild gastrointestinal discomfort, though rare allergic reactions may occur. Individuals with gallstones or bile duct obstruction should consult a physician before use. Selenium toxicity is possible with high doses, so it is essential not to exceed the recommended dosage. The supplement may interact with anticoagulants or antiplatelet drugs, increasing the risk of bleeding. Caution is advised when using it with chemotherapy or immunosuppressants, as its antioxidant effects might alter their efficacy. Monitor total antioxidant intake to avoid excessive exposure, which could interfere with treatments like chemotherapy or radiotherapy.
Store ProstaRedox in a cool, dry place, away from sunlight and moisture. When stored properly, it has a shelf life of 24 months. The supplement is manufactured according to good practices and requires no prescription.